Pair Name	Curcumol, Doxorubicin
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Gene Regulation	Down-regulation	Expression	ABCC3	hsa8714
	Up-regulation	Expression	MIR181B2	KEGG ID N.A.
	Up-regulation	Activity	NFATC2	hsa4773
In Vitro Model	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
In Vivo Model	MDA-MB-231-luc cells were suspended in a 1:1 mixture of saline/Matrigel and injected into the mammary fat pads of six-week-old female nude mice (n = 5 animals; 100 μL and 5×10⁶ cells per animal).
Result	Our study provides novel mechanistic evidence for curcumol-mediated sensitization to doxorubicin in TNBC, and it highlights the potential therapeutic usefulness of curcumol as an adjunct drug in TNBC patients with doxorubicin-resistance.